# Metabolic diseases Task Force
**Main scientific questions**
1. Evaluation of risk factors (comorbidities, genetics) associated with poor response to GLP1RA and/or progression.
2. Identification of protein biomarkers to GLP1RA medication to get insight into pathways/mechanisms, signatures across patient substrata and biomarker selection in clinical trials and medication management?
3. Evaluation of risk factors (comorbidities, genetics) for adverse events with GLP1RA treatment.
All Task Force related summary statistics can be found from: /finngen/library-green/task\_force/
All Task Force GWASes can be found from Task Force PheWeb:
More detailed Scientific proposal, meeting materials and analysis documentation can be found in [Teams here](https://helsinkifi.sharepoint.com/:f:/s/FinnGen150/EreJeL5V8ypHtzvpPnQlcTEBm2wDth2udndJxxSZWnKRRQ?e=tO3Dwa)
If you don't have access to the Teams Group, write to
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