Parkinson's disease Task Force

Chairs: Britney Milkovich (Abbvie), Mary Pat Reeve (FinnGen)

Main scientific questions

1. Identification of prodromal disease markers in PD

2. Understanding the most common trajectories in PD disease progression using clearly defined stages (prodromal stage, motor progression, progression to mild cognitive impairment, loss of independence, dysautonomia, sleep problems, depression)

3. Genetics/proteomics underlying mortality and disease progression in PD using different stages

4. Genetics underlying the age at onset in PD

5. Characterizing the HLA region in PD

All Task Force related summary statistics can be found from: /finngen/library-green/task_force/

All Task Force GWASes can be found from Task Force PheWeb: https://results.taskforce.finngen.fi/

More detailed Scientific proposal, meeting materials and analysis documentation can be found in Teams here

If you don't have access to the Teams Group, write to [e-mail].