What's new in DF14 endpoints

The changes in DF14 endpoints are listed below.

• New WIDE version endpoints created (Primary health care codes [Avohilmo] added)

  • 95 infectious disease endpoints (naming: AB1_XXX_WIDE)

  • H7_CONJUNCTIVITISACUNONATOPIC_WIDE

  • H7_EYELIDINFLAMMATION_WIDE

  • H8_NONSUPPNAS_WIDE

  • L12_ACNE_WIDE

• New WIDE version endpoints created (additional codes added)

  • AUTOHEP_WIDE

• New WIDE versions cancer endpoints created (Hospital inpatient codes [Hilmo] added)

  • C3_BONE_CARTILAGE_WIDE

  • C3_COLORECTAL_WIDE

  • C3_DIGESTIVE_ORGANS_WIDE

  • C3_ENDOCRINE_WIDE

  • C3_EYE_BRAIN_NEURO_WIDE

  • C3_FEMALE_GENITAL_WIDE

  • C3_HEAD_AND_NECK_WIDE

  • C3_MALE_GENITAL_WIDE

  • C3_MESTOTHEL_SOFTTISSUE_WIDE

  • C3_RESPIRATORY_INTRATHORACIC_WIDE

  • C3_SKIN_WIDE

  • C3_URINARY_TRACT_WIDE

  • C3_LIQUID_CANCER_WIDE

  • C3_SOLID_CANCER_WIDE

• New phenotypes created

  • Primary Sclerosing Cholangitis, IBD and UDCA required (K11_PSC)

  • Benign thyroid growths and nodules (THYGROWTHS)

  • Primary biliary cholangitis, wide definition (K11_PBC_WIDE)

  • Urinary track infection (N14_UTI_FEMALE_WIDE)

  • Malignant neoplasm (C3_SOLID_LIQUID_CANCER)

  • Malignant neoplasm, including Hilmo (C3_SOLID_LIQUID_CANCER_WIDE)

• Endpoint definition corrected:

  • M13_SLE

  • Q17_PDA

  • N14_UTER_POLYP

  • PACEMAKER

  • C3_MELANOMA

  • C3_MELANOMA_WIDE

  • INFLUENCA

  • C3_LIVER_INTRAHEPATIC_BILE_DUCTS

  • C3_LIVER_INTRAHEPATIC_BILE_DUCTS_WIDE

  • LUNG_CANCER_MESOT

  • K11_KELAIBD

  • RHEUMA_SEROPOS_WIDE

  • E4_THYROID

  • MYELOPROF

  • C3_KIDNEY_NOTRENALPELVIS_WIDE

  • C3_LIQUID_CANCER

  • C3_CANCER

  • C3_CANCER_WIDE

  • C3_SOLID_CANCER

• Renamed endpoints (definitions not changed)

  • M13_OVERLAP renamed as M13_MCTD

  • H7_OPTATROPHY renamed as H7_OPTATROPHY_WIDE

  • AB1_DIBTHERIA renamed as AB1_DIPTHERIA

  • AB1_DIBTHERIA_WIDE renamed as AB1_DIPTHERIA_WIDE

  • C3_EPENDYDOMA renamed as C3_EPENDYMOMA

  • N14_UTER_POLYP renamed as N14_CERVIC_POLYP

  • CD2_FOLLICULAR_LYMPHOMA renamed as C3_FOLLICULAR_LYMPHOMA

  • CD2_HODGKIN_LYMPHOMA renamed as C3_HODGKIN_LYMPHOMA

  • CD2_IMMUNOPROLIFERATIVE renamed as C3_IMMUNOPROLIFERATIVE

  • CD2_INDEPENDENT_MULTIPLE_SITES renamed as C3_INDEPENDENT_MULTIPLE_SITES

  • CD2_INDEPENDENT_MULTIPLE_SITES_NAS renamed as C3_INDEPENDENT_MULTIPLE_SITES_NAS

  • CD2_LEUKAEMIA_NAS renamed as C3_LEUKAEMIA_NAS

  • CD2_LYMPHOID_LEUKAEMIA renamed as C3_LYMPHOID_LEUKAEMIA

  • CD2_MONOCYTIC_LEUKAEMIA renamed as C3_MONOCYTIC_LEUKAEMIA

  • CD2_MULTIPLE_MYELOMA_PLASMA_CELL renamed as C3_MULTIPLE_MYELOMA_PLASMA_CELL

  • CD2_MYELOID_LEUKAEMIA renamed as C3_MYELOID_LEUKAEMIA

  • CD2_NEOPLASM renamed as C3_NEOPLASM

  • CD2_NONFOLLICULAR_LYMPHOMA renamed as

  • CD2_NONHODGKIN_NAS renamed as C3_NONHODGKIN_NAS

  • CD2_OTHER_LEUKAEMIA_SPECIFIED renamed as C3_OTHER_LEUKAEMIA_SPECIFIED

  • CD2_OTHER_SPECIAL_TNK_LYMPHOMA renamed as C3_OTHER_SPECIAL_TNK_LYMPHOMA

  • CD2_PRIMARY_LYMPHOID_HEMATOPOIETIC renamed as C3_PRIMARY_LYMPHOID_HEMATOPOIETIC

  • CD2_PRIMARY_LYMPHOID_HEMATOPOIETIC_NAS renamed as C3_PRIMARY_LYMPHOID_HEMATOPOIETIC_NAS

  • CD2_TNK_LYMPHOMA renamed as C3_TNK_LYMPHOMA

  • CD2_UVEAMELANOMA renamed as C3_UVEAMELANOMA

• Core endpoint status updated (WILL be part of the R14 core GWAS analyses)

  • C3_ASTROCYTOMA

  • C3_BASAL_CELL_CARCINOMA

  • C3_BREAST_HER2NEG_WIDE

  • C3_BURKITT_WIDE

  • C3_HEART_MEDIASTINUM_PLEURA_WIDE

  • C3_TONSIL_WIDE

• Core endpoint status updated (WON’T be part of the R14 core GWAS analyses)

  • AB1_DERMATOPHYTOSIS

  • AB1_ERYSIPELAS

  • AB1_HERPES_SIMPLEX

  • AB1_VIRAL_SKIN_NOS

  • AB1_ZOSTER

  • C3_BURKITT

  • C3_CIRCULATING_LYMPHOID

  • C3_DIGESTIVE_ORGANS

  • C3_ENDOCRINE

  • C3_EYE_BRAIN_NEURO

  • C3_FEMALE_GENITAL

  • C3_HEAD_AND_NECK

  • C3_MALE_GENITAL

  • C3_MEDULLOBLASTOMA

  • C3_MESTOTHEL_SOFTTISSUE

  • C3_OVARY_MUCINO

  • C3_OVARY_SEROUS

  • C3_RESPIRATORY_INTRATHORACIC

  • C3_SKIN

  • C3_SQUAMOUS_CELL_CARCINOMA_SKIN

  • C3_TONSIL

  • C3_URINARY_TRACT

  • C3_SOLID_CANCER

  • C3_LIQUID_CANCER

  • C3_WILMS_TUMOR

  • AB1_SCARLET_FEVER_WIDE

  • AB1_VIRAL_OTHER_INTEST_INFECTIONS_WIDE

• New tags added

  • CD2 tag added to 22 endpoints

  • C3 tag added to 8 endpoints

  • INSITU tag added 64 endpoints