> For the complete documentation index, see [llms.txt](https://docs.finngen.fi/llms.txt). Markdown versions of documentation pages are available by appending `.md` to page URLs; this page is available as [Markdown](https://docs.finngen.fi/finngen-data-specifics/red-library-data-individual-level-data/genotype-data/imputation-panel.md).

# Imputation Panel

## History of the SiSu Project

[The International Sequencing Initiative Suomi (SISu)](http://sisuproject.fi) Project was launched in 2011 to collect and facilitate a wider usage of Finnish whole-genome sequencing (WGS) and whole-exome sequencing (WES) datasets.

For the longest time, Finnish (and Finnophile) geneticists have been using SISu as a resource for referring to Finnish specific allele frequencies and understanding Finnish genetic architecture.

## How do we use the SiSu imputation panel?

The convenience of using FinnGen data is that the genotype data is imputed against a [Finnish specific (Sisu) imputation panel.](https://thl.fi/en/web/thl-biobank/for-researchers/sample-collections/thl-biobank-imputation-reference-panel)

The Sisu imputation panels used are described in the subsections of both

* [Sisu v4 (as of August 2021)](/finngen-data-specifics/red-library-data-individual-level-data/genotype-data/imputation-panel/sisu-v4-reference-panel.md) and
* [Sisu v3 (as of FinnGen R2)](/finngen-data-specifics/red-library-data-individual-level-data/genotype-data/imputation-panel/sisu-v3-reference-panel.md) reference panel sections