Hospital administered medications

Hospital administered medications data includes medications knwon to be given at hospitals. FinnGen has medication purchase information from Kela and Kanta registries, but medications administered at hospitals are missing from these registries (including mainly drugs administered via i.v. route).

Hospital administered medications data has two datasets, pilot and extended:

Pilot set was obtained from two hospital biobanks (Helsinki and Central Finland) and including 25 hospital administered drugs. These drugs consist mainly of biological medications used in Task Force diseases, i.v. glucocorticoids used for exacerbation for many diseases and two immuno-oncological drugs. Data can be found from: /finngen/library-red/Hospital_Administered_Medications/finngen_R12_hospital_medications_1.0.txt

Extended hospital administered medications dataset has data from all six hospital biobanks and includes 15 medications in total. These consist of 11 biological drugs relevant for Task Forces and 4 immuno-oncological drugs. Data can be found from: /finngen/library-red/Hospital_Administered_Medications/Hospital_Admister_Medications_Extended/.

Number of FINNGENIDs: 10108 Number of rows: 166231

Incuded drugs are:

abatacept anifrolumab atezolizumab belimumab guselkumab infliximab ipilimumab nivolumab pembrolizumab reslizumab risankizumab rituximab tocilizumab ustekinumab vedolizumab

VARIABLE DESCRIPTION

FINNGENID Studyid

COHORT_DATA Cohort or biobank that sent the data

DRUG_NAME Name of the medicine

ATC_CODE ATC code of the medicine

APPROX_ADMINISTRATION_DATE Randomized administration date (randomized +/- 1-15 days from the exact date)

EVENT_AGE_ADMINISTRATION Age at the time of administration

APPROX_PRESCRIPTION_DATE Randomized prescription date (randomized +/- 1-15 days from the exact date). If it's not clear if the date is for actual administration, not just prescription made at the hospital, then prescription data has been used by biobanks

EVENT_AGE_PRESCRIPTION Age at the time of prescription

FOUND_IN_KANTAPRESCRIPTION The information can also be found in the Kanta prescription data based on FINNGENID, ACT_CODE, PRESCRIPTION_DATE and ADMINISTRATION_DATE, 1=yes, NA=no or uncertain