Metabolomics

The data below were generated as part of the FinnGen 2 Expansion Area 5 (EA5) pilot. For this analysis, we used Metabolon's Global Discovery Panel that covers 5,400+ metabolites.

We have analyzed a subset of 1,000 blood donor individuals (in two batches) using the Olink 3K and SomaScan 7K proteomics platforms.

The raw data is available in the Sandbox in:

/finngen/library-red/EA5/metabolomics/raw_data/batch2/HELS-0102-21PHML+ MERGED DATA TABLES (FILE 2 OF 3) .XLSX under the sheet "Batch-norm Data All" and with imputed missing data under "Batch-norm Data All wImp".

A ready-to-use file connecting the raw data to FINNGENIDs (66/1000 samples do not have a FINNGENID) and sample timestamps is available here:

/finngen/library-red/EA5/metabolomics/final/EA5_Metabolomics_data.tsv

and the metabolites annotation can to chemical names and pathways can be found in:

/finngen/library-red/EA5/metabolomics/raw_data/HELS-01-21ML+DATA_TABLES.XLSX under the sheet "Chemical Annotation".

No mQTL analysis has been performed so far.