# Finnish Registry for Kidney Diseases

### Sandbox directory

The data is available in the following Sandbox directory:

`/finngen/library-red/finngen_R[RELEASE]/kidney_disease_register_1.0`

Please refer to the readme file in the sandbox directory for full details of the available data.

**Note, this data also available in Atlas and OMOP common data model.**

### Description

The [Finnish Registry for Kidney Diseases](https://www.muma.fi/liitto/suomen_munuaistautirekisteri/finnish_registry_for_kidney_diseases) has comprehensive coverage of dialysis and kidney transplantation patients in Finland. FinnGen data consists of FinnGen participants with dialysis from kidney transplants in Finland since 1964.

### Variables

Diagnoses behind kidney diseases (finngen\_R12\_kidney\_disease\_register):

<table data-header-hidden><thead><tr><th width="376.551724137931"></th><th></th></tr></thead><tbody><tr><td>FINNGENID</td><td>Study id</td></tr><tr><td>EVENT_AGE</td><td>Age at the time of the event (some kidney disease)</td></tr><tr><td>KIDNEYREG_T1DM</td><td>Type 1 diabetes with a causal role to some kidney disease. E10</td></tr><tr><td>KIDNEYREG_T2DM</td><td>Type 2 diabetes with a causal role to some kidney disease. E11</td></tr><tr><td>KIDNEYREG_POLYCYS</td><td>Polycystic kidney disease. Q61[1-3]</td></tr><tr><td>KIDNEYREG_GLOMNEPH</td><td>Glomerulonephritis. NO[0|1|3]</td></tr><tr><td>KIDNEYREG_NEPHROSCLER</td><td>Nephrosclerosis. 112|113|1701|N280</td></tr><tr><td>KIDNEYREG TUBULOINT</td><td>Tubulointerstitial nephritis. N1[0-2]</td></tr><tr><td>KIDNEYREG_AMYLOIDOSIS</td><td>Amyloidosis. E85</td></tr><tr><td>KIDNEYREG_ACTIVE</td><td>Active kidney disease therapy = All patients in the kidney disease register data.</td></tr></tbody></table>

Kidney disease register, Incidence (finngen\_R12\_kidney\_disease\_register\_incidence):

| FINNGENID                                       | Study id                                                                                                                                                                                                   |
| ----------------------------------------------- | ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- |
| EVENT\_AGE                                      | Age at the time of event (Start of active treatment)                                                                                                                                                       |
| APPROX\_EVENT\_DAY                              | Date of the event (+/- 15 days)                                                                                                                                                                            |
| START\_YEAR                                     | Year of the start of active treatment                                                                                                                                                                      |
| KIDNEY\_DISEASE\_DIAGNOSIS\_1                   | Diagnosis 1                                                                                                                                                                                                |
| KIDNEY\_DISEASE\_DIAGNOSIS\_2                   | Diagnosis 2                                                                                                                                                                                                |
| ERA\_EDTA\_DIAGNOSIS                            | ERA EDTA Diagnosis                                                                                                                                                                                         |
| EDTA\_DIAGNOSIS\_OLD                            | Old EDTA Diagnosis                                                                                                                                                                                         |
| APPROX\_END\_DATE\_OF\_TRACKING                 | Date of end of tracking (+/-15 days). This variable contained whole numbers. Those were transformed to date using 1899-12-30 as origin (excel).                                                            |
| END\_OF\_TRACKING\_AGE                          | Age at the time of end of tracking                                                                                                                                                                         |
| HEIGHT                                          | Height                                                                                                                                                                                                     |
| WEIGHT                                          | Weight                                                                                                                                                                                                     |
| SYSTOLIC\_BLOOD\_PRESSURE                       | Systolic blood pressure                                                                                                                                                                                    |
| DIASTOLIC\_BLOOD\_PRESSURE                      | Diastolic blood pressure                                                                                                                                                                                   |
| CHOLESTEROL                                     | Cholesterol                                                                                                                                                                                                |
| HDL\_CHOLESTEROL                                | HDL cholesterol                                                                                                                                                                                            |
| TRIGLYCERIDE                                    | Triglycerides                                                                                                                                                                                              |
| PREVIOUS                                        | Previous smoker (0=No, 1=Yes)                                                                                                                                                                              |
| CURRENT                                         | Current smoker (0=No, 1=Yes)                                                                                                                                                                               |
| APPROX\_START\_DATE\_OF\_NERF\_TRACKING         | Start date of nerf tracking                                                                                                                                                                                |
| START\_OF\_NERF\_TRACKING\_AGE                  | Age at the time of nerf tracking                                                                                                                                                                           |
| ANGINA\_PECTORIS                                | Angina pectoris (0=No, 1=Yes)                                                                                                                                                                              |
| HEART\_ATTACK                                   | Heart attack (0=No, 1=Yes)                                                                                                                                                                                 |
| BYPASS\_OR\_OTHER\_PROCEDURE                    | Bypass or other procedure (0=No, 1=Yes)                                                                                                                                                                    |
| LEFT\_VENTRICULAR\_HYPERTROPHY                  | Left venticular hypertrophy (0=No, 1=Yes)                                                                                                                                                                  |
| HEART\_FAILURE                                  | Heart failure (0=No, 1=Yes)                                                                                                                                                                                |
| OTHER\_VASCULAR\_DISEASE                        | Other vascular disease (0=No, 1=Yes)                                                                                                                                                                       |
| OTHER\_VASCULAR\_DISEASE\_ENTRY                 | Other vascular disease entry (0=No, 1=Yes)                                                                                                                                                                 |
| OTHER\_VASCULAR\_DISEASE\_AMPUTATION            | Other vascular disease amputation (0=No, 1=Yes)                                                                                                                                                            |
| DYSLIPIDEMIA\_DIET\_TREATMENT                   | Dyslipidemia diet treatment (0=No, 1=Yes)                                                                                                                                                                  |
| DYSLIPIDEMIA\_MEDICAL\_TREATMENT                | Dyslipidemia medical treatment (0=No, 1=Yes)                                                                                                                                                               |
| STROKE                                          | Stroke (0=No, 1=Yes)                                                                                                                                                                                       |
| RR\_MEDICAL\_TREATMENT                          | RR medical treatment (0=No, 1=Yes)                                                                                                                                                                         |
| T1D                                             | Type 1 diabetes (0=No, 1=Yes)                                                                                                                                                                              |
| T2D                                             | Type 2 diabetes (0=No, 1=Yes)                                                                                                                                                                              |
| UNKNOWN\_TYPE\_OF\_DIABETES                     | Unknown type of diabetes (0=No, 1=Yes)                                                                                                                                                                     |
| IV\_IRON                                        | IV Iron (0=No, 1=Yes)                                                                                                                                                                                      |
| VITAMIN\_D\_TREATMENT                           | Vitamin d treatment (0=No, 1=Yes)                                                                                                                                                                          |
| EPO\_TREATMENT                                  | EPO treatment (0=No, 1=Yes)                                                                                                                                                                                |
| FISTULA\_IN\_FIRST\_DIALYSIS\_TREATMENT         | Fistula in first dialysis treatment (1=Fistula, 2=Tunneled catheter, 3=Temporary catheter, 4=Graft)                                                                                                        |
| APPROX\_DATE\_OF\_DISCOVERING\_DIABETES         | Date of discovering diabetes (+/- 15 days)                                                                                                                                                                 |
| DISCOVERING\_DIABETES\_AGE                      | Age at the time of discovering diabetes                                                                                                                                                                    |
| REASON\_FOR\_TERMINATION\_OF\_ACTIVE\_TREATMENT | Reason for termination of active treatment (Alive in treatment, Treatment terminated, uremic, Died during treatment, Own kidney function, treatment < 3 months, Own kidney function, treatment > 3 months) |

Kidney disease register, Prevalence (finngen\_R12\_kidney\_disease\_register\_prevalence):

<table data-header-hidden><thead><tr><th width="374.9357326478149">FINNGENID</th><th>Study id</th></tr></thead><tbody><tr><td>FINNGENID</td><td>Study id</td></tr><tr><td>YEAR</td><td>Year</td></tr><tr><td>FISTULA</td><td>Fistula (1=Fistula, 2=Graft, 3=Katheter)</td></tr><tr><td>ANTIHYPERTENSIVE_DRUG</td><td>Antihypertensive drug (0=No, 1=Yes)</td></tr><tr><td>ESA_TREATMENT</td><td>ESA treatment (0=No, 1=Yes)</td></tr><tr><td>IV_IRON</td><td>IV iron (0=No ,1=Yes)</td></tr><tr><td>DIALYSIS_PER_WEEK</td><td>Number of dialysis treatments per week</td></tr><tr><td>DIALYSIS_H_PER_WEEK</td><td>Dialysis treatment time in hours per week</td></tr><tr><td>AZATHIOPRINE</td><td>Azatioprine (0=No, 1=Yes)</td></tr><tr><td>CICLOSPORIN</td><td>Ciclosporin (0=No, 1=Yes)</td></tr><tr><td>TACROLIMUS</td><td>Tacrolimus (0=No, 1=Yes)</td></tr><tr><td>MYCOPHENOLATE</td><td>Mycophenolate (0=No, 1=Yes)</td></tr><tr><td>STEROIDS</td><td>Streroids (0=No, 1=Yes)</td></tr><tr><td>OTHER_IMMUNOSUPPRESSIVE</td><td>Other immunosuppressive medication (0=No, 1=Yes)</td></tr><tr><td>ON_TRANSFER_LIST_OR_NOT</td><td>On transfer list or not (0=No, 1=Yes)</td></tr><tr><td>PRODUCTION_OF_URINE</td><td>Production of urine</td></tr><tr><td>PERITONITIS_PER_YEAR</td><td>Number of peritonitis per year</td></tr><tr><td>T1D</td><td>Type 1 diabetes (0=No, 1=Yes)</td></tr><tr><td>T2D</td><td>Type 2 diabetes (0=No, 2=Yes)</td></tr><tr><td>UNKNOWN_TYPE_OF_DIABETES</td><td>Unknown type of diabetes (0=No, 3=Yes)</td></tr><tr><td>DIABETES_AGE</td><td>Age at diabetes diagnosis</td></tr><tr><td>APPROX_DIABETES_DATE</td><td>Date of diabetes diagnosis (+/- 15 days)</td></tr></tbody></table>

Kidney disease register, Treatment history (finngen\_R12\_kidney\_disease\_register\_treatment\_history):

<table data-header-hidden><thead><tr><th width="376.9357326478149">FINNGENID</th><th>Study id</th></tr></thead><tbody><tr><td>FINNGENID</td><td>Study id</td></tr><tr><td>EVENT_AGE</td><td>Age at the time of event (treatment change)</td></tr><tr><td>APPROX_EVENT_DAY</td><td>Approximated date of treatment change (+/-15 days)</td></tr><tr><td>PREVIOUS_FORM_OF_TREATMENT</td><td>Previous form of treatment (*listed below)</td></tr><tr><td>CURRENT_FORM_OF_TREATMENT</td><td>Current form of treatment (*listed below)</td></tr><tr><td>TYPE_OF_CHANGE</td><td>Categorical type of change (T=Change in the form of treatment, H= Change of hospital, D=Death, NA=New patient)</td></tr></tbody></table>

{% hint style="info" %}
More information about the data is available from the [Finnish Registry for Kidney Diseases](https://www.muma.fi/liitto/suomen_munuaistautirekisteri/finnish_registry_for_kidney_diseases).
{% endhint %}


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