Hilmo and avohilmo extended data

Details on the extended Hilmo and Avohilmo data containing anthropometric measures, smoking an alcohol use, blood pressure measurements and long-term (chronic) conditions.

Introduction

Starting from release 13 (R13), additional longitudinal data from Avohilmo (primary care) and Hilmo (hospital inpatient and outpatient) registers has been collated and released into sandbox. The purpose of this data is to provide, in one file, additional context on FinnGen individuals that can be useful in epidemiological and genetic analyses.

Sandbox directory

The data is available in the following Sandbox directories:

• R14: /finngen/library-red/finngen_R14/hilmo_avohilmo_extended_1.0/

• R13: /finngen/library-red/finngen_R13/hilmo_avohilmo_extended_1.0/

The readme file in these directories provides full details of the available data and the meaning of each variable.

Description

The data files contain the following information from the Hilmo inpatient and outpatient registers (INPAT, OUTPAT) and the Avohilmo primary care register (PRIM_OUT):

• Weight (kg)

• Height (cm)

• BMI

• Smoking code

• Audit test results (10 questions)

• Systolic and diastolic blood pressure (mmHg)

• Long term diagnosis (ICD10-codes)

Note: In some cases (most often seen in PRIM_OUT - primary care), the same measurement has been recorded multiple times on the same day - these entries look identical but will have a different INDEX (see table below). As this may impact some analyses, we recommend filtering or deduplicating the data using APPROX_EVENT_DAY so only of the identical measurements are selected per day.

Field	Description
FINNGENID	Study ID
SOURCE	Source register
EVENT_AGE	Age at the event
APPROX_EVENT_DAY	Randomized event day (within +/- 1-15 days)
CODE1-10	Register source specific codes and other information
CATEOGORY	Code sequence number
INDEX	Register specific index number of entries

Definitions

SMOKING

• 1 Smokes daily

• 2 Smokes occasionally but significantly

• 3 Significant passive smoking

• 4 No significant tobacco exposure

• 5 Significant smoking or exposure has ceased

• 6 Never smoked or had significant exposure

• 9 No information on smoking and exposure

AUDIT_FULL

• 0-5: the risks are low

• 6-10: risks slightly increased

• 11-14: risks have clearly increased

• 20-40: the risks are very high

ARRIVAL_MODE

• 1 Emergency

• 2 Appointment

• 3 Transfer from clinic to inpatient care

• 4 Intra-hospital transfer

• 5 Inter-hospital transfer

• 6 Unknown (mainly in use only 2007-2010, definition was not found)

• 9 Other