# Data Releases 2021

**27 December 2021**

* Finngen R8 service sector detailed data
* These data files contain:
  * Information about service sector, specialty and contact type from the Hilmo inpatient and outpatient register, and primary health care register
  * Information about drug reimbursement costs from the kela drug purchase register.
* Data and documentation location in Sandbox:
  * /finngen/library-red/finngen\_R8/service\_sector\_detailed\_1.0/
* Detailed paths to library red data from catalog:
  * /finngen/library-red/finngen\_R8/catalog/catalog.txt

**20 December 2021**

* FinnGen R8 vaccination register data (version 2.0)
  * The data contains vaccination data of 316 551 FinnGen participants.
* Data and documentation location in Sandbox:
  * /finngen/library-red/finngen\_R8/vaccination\_register\_2.0/
* Detailed paths to library red data from catalog:
  * /finngen/library-red/finngen\_R8/catalog/catalog.txt

**20 December 2021**

* infectious disease register data (corona, version 3.0)
  * The data contains 7058 (cumulative number) corona virus positive FinnGen participants.
* Data and documentation location in Sandbox:
  * /finngen/library-red/finngen\_R8/infectious\_disease\_register\_corona\_3.0/
* Detailed paths to library red data from catalog:
  * /finngen/library-red/finngen\_R8/catalog/catalog.txt

**20 December 2021**

* Lists of significant coding variant associations for all analyzed endpoints in FinnGen R8
* Data in the green library:
  * Data location in Google cloud: gs\://finngen-production-library-green/finngen\_R8/finngen\_R8\_analysis\_data/summary\_stats/coding\_variants/
  * Data location in Sabox: /finngen/library-green/finngen\_R8/finngen\_R8\_analysis\_data/summary\_stats/coding\_variants/
* Documentation in the green library:
  * Data location in Google cloud: gs\://finngen-production-library-green/finngen\_R8/finngen\_R8\_analysis\_data/summary\_stats/coding\_variants/README
  * Data location in Sabox: /finngen/library-green/finngen\_R8/finngen\_R8\_analysis\_data/summary\_stats/coding\_variants/README

**17 December 2021**

* FinnGen R8 chip data (version 1.0)
* Data and documentation location in Sandbox:
  * /finngen/library-red/finngen\_R8/chipd\_1.0/
* Detailed paths to library red data from catalog:
  * /finngen/library-red/finngen\_R8/catalog/catalog.txt

**29 November 2021**

* FinnGen release 8 and UKBB meta-analysis results
* Data in green library:
  * Data location in Google cloud: gs\://finngen-production-library-green/finngen\_R8/finngen\_R8\_analysis\_data/ukbb\_meta/
  * Data location in Sabox: /finngen/library-green/finngen\_R8/finngen\_R8\_analysis\_data/ukbb\_meta/
* Documentation in green library:
  * Data location in Google cloud: gs\://finngen-production-library-green/finngen\_R8/finngen\_R8\_analysis\_data/ukbb\_meta/readme
  * Data location in Sabox: /finngen/library-green/finngen\_R8/finngen\_R8\_analysis\_data/ukbb\_meta/readme

**26 November 2021**

* SISuv4 LDstore correlation (BCOR) files
* Data in green library:
  * Data location in Google cloud: gs\://finngen-production-library-green/imputation\_panel/v4/LD/
  * Data location in Sabox: /finngen/library-green/imputation\_panel/v4/LD/
* Documentation in green library:
  * Data location in Google cloud: gs\://finngen-production-library-green/imputation\_panel/v4/LD/README.md
  * Data location in Sabox: /finngen/library-green/imputation\_panel/v4/LD/README.md

**24 November 2021**

* FinnGen R8 parental causes of death data (version 1.0)
* A description for this data can be found in [Other registry data files](https://docs.finngen.fi/finngen-data-specifics/red-library-data-individual-level-data/what-phenotype-files-are-available-in-sandbox-1/other-registers).
* Number of unique FINNGENIDs: 262 248
* Data and documentation location in Sandbox:
  * /finngen/library-red/finngen\_R8/parental\_causes\_of\_death\_1.0/
* Detailed paths to library red data from catalog:
  * /finngen/library-red/finngen\_R8/catalog/catalog.txt

**23 November 2021**

* FinnGen R8 visual impairment data (version 1.0)
* This data contains information from the Finnish Register of Visual impairment. Data description can be found in [Other registry data files](https://docs.finngen.fi/finngen-data-specifics/red-library-data-individual-level-data/what-phenotype-files-are-available-in-sandbox-1/other-registers).
* Number of unique FINNGENIDs: 2401
* Data and documentation location in Sandbox:
  * /finngen/library-red/finngen\_R8/visual\_impairment\_register\_1.0/
* Detailed paths to library red data from catalog:
  * /finngen/library-red/finngen\_R8/catalog/catalog.txt

**15 November 2021**

* R8 core analyses:
* FinnGen R8 GWAS analysis data
  * Updated version of regenie
  * These files contain the summary statistics for R8 core endpoints as well as manhattan plot images
  * Data in green library:
    * /finngen/library-green/finngen\_R8/finngen\_R8\_analysis\_data/summary\_stats
* FinnGen R8 Fine-mapping analysis data
  * These files contain the finemapping results for R8 core endpoints, performed using SUSIE and FINEMAP
  * Data in green library:
    * /finngen/library-green/finngen\_R8/finngen\_R8\_analysis\_data/finemap
  * Documentation in green library:
    * /finngen/library-green/finngen\_R8/finngen\_R8\_analysis\_documentation/
* FinnGen R8 Autoreporting data
  * These files contain the autoreporting summaries created from finemapping & GWAS summary statistic data
  * Data in green library:
    * /finngen/library-green/finngen\_R8/finngen\_R8\_analysis\_data/autoreporting
  * Documentation in green library:
    * /finngen/library-green/finngen\_R8/finngen\_R8\_analysis\_documentation/
* FinnGen R8 Colocalization data
  * Colocalization between FinnGen SUSIE fine-mapping and multiple other resources
  * Data and documentation in green library:
    * /finngen/library-green/finngen\_R8/finngen\_R8\_analysis\_data/colocalization
* This data is also available for browsing in Pheweb: <https://results.finngen.fi>

**15 November 2021**

* The covariates and endpoints used in R8 core analyses.
* R8\_COV\_PHENO\_V4\_1.txt.gz and R8\_COV\_PHENO\_V4\_1.FID.txt.gz contain the same data with different IDs
* Data location in Sandbox:
  * /finngen/library-red/finngen\_R8/analysis\_covariates/finngen\_R8\_cov\_1.0.txt.gz
  * /finngen/library-red/finngen\_R8/analysis\_covariates/finngen\_R8\_COV\_PHENO\_V4\_1.txt.gz
  * /finngen/library-red/finngen\_R8/analysis\_covariates/finngen\_R8\_COV\_PHENO\_V4\_1.FID.txt.gz

**15 November 2021**

* Finngen R8 cluster plot data
* These data files contain genotype intensities per variant for a subset of samples that are used in cluster plots (released in the green library).
* Data and documentation location in Sandbox:
  * /finngen/library-red/finngen\_R8/cluster\_plot\_1.0/
* See the detailed path of this data from manifest:
  * /finngen/library-red/finngen\_R8/cluster\_plot\_1.0/manifest.txt

**4 November 2021**

* FinnGen R8 PRS data
* Data and documentation location in Sandbox:
  * /finngen/library-red/finngen\_R8/prs\_1.0/
* Detailed paths to library red data from catalog:
  * /finngen/library-red/finngen\_R8/catalog/catalog.txt

**25 October 2021**

* FinnGen R8 kidney disease register data
* Data and documentation location in Sandbox:
  * /finngen/library-red/finngen\_R8/kidney\_disease\_register\_1.0/
* Detailed paths to library red data from catalog:
  * /finngen/library-red/finngen\_R8/catalog/catalog.txt

**20 October 2021**

* GRM, bgen chunks, and analysis covariates for custom analyses
* Data and documentation locations in Sandbox:
  * library-red/finngen\_R8/grm\_1.0/
  * library-red/finngen\_R8/bgen\_1.0\_20k\_chunks
  * library-red/finngen\_R8/analysis\_covariates/

**13 October 2021**

* FinnGen R8 phenotype data (version 4.0)
* This data has been created with an updated version of Endpointter and new definition files. These changes corrected the controls of some endpoints.
* Data and documentation location in Sandbox:
  * /finngen/library-red/finngen\_R8/phenotype\_4.0
* Detailed paths to library red data from catalog:
  * /finngen/library-red/finngen\_R8/catalog/catalog.txt

**7 October 2021**

* tsv file mapping alleles between SISuv3 and SISuv4 panel released to green library
* The file is available in both v3 and v4 panel subfolders (the file is identical in both locations)
* Location in v3 panel subfolders
  * in Google cloud: gs\://finngen-production-library-green/imputation\_panel/v3/annotation/map\_v3\_v4\_alleles\_v2.tsv
  * in Sandbox: /finngen/library-green/imputation\_panel/v3/annotation/map\_v3\_v4\_alleles\_v2.tsv
* Location in v4 panel subfolders
  * in Google cloud: gs\://finngen-production-library-green/imputation\_panel/v4/annotation/map\_v3\_v4\_alleles\_v2.tsv
  * in Sandbox: /finngen/library-green/imputation\_panel/v4/annotation/map\_v3\_v4\_alleles\_v2.tsv

**7 October 2021 (edit: Aug 2024 - meta-analysis results with Estonian biobank are no longer available)**

* The meta-analysis results between FinnGen (release 7), UKBB and Estonia Biobank for 50 phenotypes have been released in the green library:
  * Data location in Google cloud: gs\://finngen-production-library-green/finngen\_R7/finngen\_R7\_analysis\_data/ukbb\_estbb\_meta/
  * Data location in Sandbox: /finngen/library-green/finngen\_R7/finngen\_R7\_analysis\_data/ukbb\_estbb\_meta/
* The results include summary statistics from meta-analysis (including leave-one-out results) and autoreporting results. Please see the readme for more information:
  * Readme location in Google cloud: gs\://finngen-production-library-green/finngen\_R7/finngen\_R7\_analysis\_data/ukbb\_estbb\_meta/README.md
  * Readme location in Sandbox: /finngen/library-green/finngen\_R7/finngen\_R7\_analysis\_data/ukbb\_estbb\_meta/README.md

**6 October 2021**

* Finnish nationwide breast and cervical cancer screening data (cancer\_screening\_1.0) and
* Detailed version of Finnish cancer register data (cancer\_detailed\_1.0)
* Data and documentation location in Sandbox:
  * /finngen/library-red/finngen\_R8/cancer\_screening\_1.0
  * /finngen/library-red/finngen\_R8/cancer\_detailed\_1.0
* Detailed paths to library red data from catalog:
  * /finngen/library-red/finngen\_R8/catalog/catalog.txt

**4 October 2021**

* FinnGen R8 imputed STR data (version 1.0)
* Data and documentation location in Sandbox:
  * /finngen/library-red/finngen\_R8/imputed\_str\_1.0/
* Detailed paths to library red data from catalog:
  * /finngen/library-red/finngen\_R8/catalog/catalog.txt

**30 September 2021**

* FinnGen R8 infectious disease register corona data (version 2.0)
* Data contains 5372 (cumulative number) corona virus positive FinnGen participants
* Data and documentation location in Sandbox:
  * /finngen/library-red/finngen\_R8/infectious\_disease\_register\_corona\_2.0/
* Detailed paths to library red data from catalog:
  * /finngen/library-red/finngen\_R8/catalog/catalog.txt

**29 September 2021**

* FinnGen R8 vaccination register data (version 1.0)
* Vaccination data of 249 066 FinnGen participants
* Data and documentation location in Sandbox:
  * /finngen/library-red/finngen\_R8/vaccination\_register\_1.0/
* Detailed paths to library red data from catalog:
  * /finngen/library-red/finngen\_R8/catalog/catalog.txt

**23 September 2021**

* FinnGen R8 reproductive history data (version 1.0)
* Reproductive history of 151 109 FinnGen mother participants
* The data combines information from population register (DVV) (since 1953) and medical birth register (since 1987).
* Data and documentation location in Sandbox:
  * /finngen/library-red/finngen\_R8/birth\_and\_dvv\_register\_1.0/
* Detailed paths to library red data from catalog:
  * /finngen/library-red/finngen\_R8/catalog/catalog.txt

**22 September 2021**

* FinnGen R8 phenotype 3.0 data
* Created using an updated version of Endpointter.
* Years 2020 and 2021 added to Hilmo registers (preliminary information).
* Data and documentation location in Sandbox:
  * /finngen/library-red/finngen\_R8/phenotype\_3.0/

**6 September 2021**

* Finngen R8 genotype plink conversion data (version 1.0) and
* PCA-kinship data (version 1.0)
* Data and documentations location in Sandbox:
  * R8 genotype plink data and documentation: /finngen/library-red/finngen\_R8/genotype\_plink\_1.0/
  * R8 PCA data and documentation:/finngen/library-red/finngen\_R8/pca\_1.0/
  * R8 prune data and documentation:/finngen/library-red/finngen\_R8/prune\_1.0/
  * R8 kinship data and documentation: /finngen/library-red/finngen\_R8/kinship\_1.0

**6 September 2021**

* FinnGen R8 detailed longitudinal phenotype data
* Data location in Sandbox: /finngen/library-red/finngen\_R8/phenotype\_2.0
* New: codes with <5 cases have not been removed from this data

**30 August 2021**

* FinnGen R8 infectious disease register corona (version 1.0) data
* This data contains 4808 (cumulative number) corona virus positive FinnGen participant
* Data location in Sandbox: /finngen/library-red/finngen\_R8/infectious\_disease\_register\_corona\_1.0/

**27 August 2021**

* FinnGen release 8 genotype and phenotype data
* Finngen R8 data was imputed using SISuV4 reference panel that contains 8,554 high coverage \[25x] WGS Finnish individuals.
* The current data statistics are:\
  Number of individuals with genotypes = 356 213

  Number of individuals with endpoints = 356 077\
  Number of imputed variants = 20 175 454\
  Number of endpoints = 4228
* Genotypes Data & Documentation location in Sandbox: /finngen/library-red/finngen\_R8/genotype\_1.0/
* Phenotypes Data & Documentation location in Sandbox: /finngen/library-red/finngen\_R8/phenotype\_2.0/ (note that phenotype\_1.0 was an internal release only)
* See the detailed paths to library red data from catalog: /finngen/library-red/finngen\_R8/catalog/catalog.txt

**29 June 2021**

* FinnGen R6 mosaic chromosomal alteration (version 1.0)
* Data location in Sandbox: /finngen/library-red/finngen\_R6/mca\_1.0/

**22 June 2021**

* FinnGen R7 Colocalization
* Data location in Google cloud: gs\://finngen-production-library-green/finngen\_R7/finngen\_R7\_analysis\_data/colocalization/
* Data location in Sabox: /finngen/library-green/finngen\_R7/finngen\_R7\_analysis\_data/colocalization/

**22 June 2021**

* FinnGen R7 Autoreporting
* Data location in Google cloud: gs\://finngen-production-library-green/finngen\_R7/finngen\_R7\_analysis\_data/autoreporting/
* Data location in Sabox: /finngen/library-green/finngen\_R7/finngen\_R7\_analysis\_data/autoreporting/

**22 June 2021**

* FinnGen R7 finemapping results
* Data location in Google cloud: gs\://finngen-production-library-green/finngen\_R7/finngen\_R7\_analysis\_data/finemap/
* Data location in Sandbox: /finngen/library-green/finngen\_R7/finngen\_R7\_analysis\_data/finemap/

**3 June 2021**

* FinnGen R7 infectious disease register corona (version 4.0)
* This data contains 3496 (cumulative number) corona virus positive FinnGen participants
* Data location in Sandbox: /finngen/library-red/finngen\_R7/infectious\_disease\_register\_corona\_4.0/

**10 May 2021**

* FinnGen R7 infectious disease register corona (version 3.0)
* This data contains 3356 (cumulative number) corona virus positive FinnGen participants.
* Data location in Sandbox: /finngen/library-red/finngen\_R7/infectious\_disease\_register\_corona\_3.0/

**3 May 2021**

* FinnGen R7 kidney disease register data (version 1.0)
* Data location in Sandbox: /finngen/library-red/finngen\_R7/kidney\_disease\_register\_1.0

**30 April 2021**

* FinnGen R7 detailed cancer data (version 1.0)
* Data location in Sandbox: /finngen/library-red/finngen\_R7/cancer\_detailed\_1.0/

**29 April 2021**

* FinnGen R7 parental endpoint data (version 2.0)
* Data locationin Sandbox: /finngen/library-red/finngen\_R7/parental\_endpoint\_2.0

**27 April 2021**

* FinnGen R7 prs data (version 1.0)
* Data location in Sandbox: /finngen/library-red/finngen\_R7/prs\_1.0/

**27 April 2021**

* FinnGen R7 parental endpoint data (version 1.0)
* Data locationin Sandbox: /finngen/library-red/finngen\_R7/parental\_endpoint\_1.0

**26 April 2021**

* FinnGen R7 GRM data (version 1.0)
* Data location in Sandbox: /finngen/library-red/finngen\_R7/grm\_1.0

**20 April 2021**

* FinnGen R7 cov\_pheno and cov data (version 1.0)
* Data location in Sandbox: /finngen/library-red/finngen\_R7/phenotype\_4.0/

**20 April 2021**

* Finngen R7 Chip data
* In addition to the normal release dataset, it also includes high-quality filtered merged data.
* Data location in Sandbox: /finngen/library-red/finngen\_R7/chipd\_1.0/

**9 April 2021**

* FinnGen R7 corona data (version 2.0)
* This data contains 2983 (cumulative number) corona virus positive FinnGen participants.
* Data location in Sandbox: /finngen/library-red/finngen\_R7/infectious\_disease\_register\_corona\_2.0/

**30 March 2021**

* FinnGen R7 vaccination register data (version 1.0)
* The data contains vaccination data of 201 707 FinnGen participants
* Data location in Sandbox: /finngen/library-red/finngen\_R7/vaccination\_register\_1.0/

**21 March 2021**

* FinnGen R7 phenotype data (version 4.0) to Sandbox
* Number of endpoints: 4137 Number of FinnGen IDs: 321 302. Updated control definition file and made & AND rule and NEVT bug fixes to Endpointter
* Data location in Sandbox: /finngen/library-red/finngen\_R7/phenotype\_4.0

**12 March 2021**

* FinnGen R7 reproductive history data (version 1.0)
* The data contains reproductive history of 137 713 FinnGen mother participants. The data combines information from population register (DVV) (since 1953) and Medical birth register (since 1987).
* Data location in Sandbox: /finngen/library-red/finngen\_R7/birth\_and\_dvv\_register\_1.0

**12 March 2021**

* FinnGen R7 phenotype data (version 3.0)
* We have used updated endpoint and control definition files and made a few bug fixes to Endpointter. We have also filtered out some negative ages that were present in the previous first event file. Number of endpoints: 4137 Number of FinnGen IDs: 321 302
* Data location in Sandbox: /finngen/library-red/finngen\_R7/phenotype\_3.0

**9 March 2021**

* FinnGen infectious disease register data (corona, version 1.0) released to Sandbox.
* This data consists of 2560 (cumulative number) corona virus positive FinnGen participants.
* Data location in Sandbox: /finngen/library-red/finngen\_R7/infectious\_disease\_register\_corona\_1.0/

**5 March 2021**

* FinnGen visual impairment register data released to Sandbox.
* Data location in Sandbox: /finngen/library-red/finngen\_R7/visual\_impairment\_register\_1.0

**2 March 2021**

* FinnGen parental causes of death data released to Sandbox
* Data location in Sandbox: /finngen/library-red/finngen\_R7/parental\_causes\_of\_death\_1.0/

**2 March 2021**

* Finngen R7 bgen data
* Data location in Sandbox: /finngen/library-red/finngen\_R7/bgen\_2.0/

**26 February 2021**

* Finnish nationwide breast and cervical cancer screening
* Data location in Sandbox: /finngen/library-red/finngen\_R7/cancer\_screening\_1.0

**24 February 2021**

* Finngen R7 bgen data
* Data location in Sandbox: /finngen/library-red/finngen\_R7/bgen\_1.0/

**23 February 2021**

* Plink converted DF7 genotypes
* Data location in Sandbox: /finngen/library-red/finngen\_R7/genotype\_plink\_2.0

**19 February 2021**

* DF7 phenotypes
* Statistics for genotype\_2.0 and phenotype\_2.0 are: Number of endpoints: 4 145 Number of FinnGen IDs in phenotype data: 321 302 Number of FinnGen IDs in genotype data: 321 464
* Data location in Sandbox: /finngen/library-red/finngen\_R7/phenotype\_2.0

**5 February 2021**

* FinnGen R6 corona data (version 7.0)
* This data contains 1515 (cumulative number) corona virus positive FinnGen participants.
* Data location in Sandbox: /finngen/library-red/finngen\_R6/corona\_7.0/

**12 January 2021**

* FinnGen R6 corona data (version 6.0)
* Data location in Sandbox: /finngen/library-red/finngen\_R6/corona\_6.0/