# LD browser

[Linkage disequilibrium](/background-reading/linkage-disequilibrium-ld.md) server, for finding variants in LD with variant of interest. More on ld\_server on [github](https://github.com/FINNGEN/ld_server).

### Example:

* variant= `6:44693011:A:G`
* window=`1000000`
* reference panel: `sisu42` and
* ld threshold = `0.9`:

`http://api.finngen.fi/api/ld?variant=6:44693011:A:G&window=1000000&panel=sisu42&r2_thresh=0.9`

{% embed url="<http://api.finngen.fi/api/ld?variant=6:44693011:A:G&window=1000000&panel=sisu42&r2_thresh=0.9>" %}

You can get the variants in LD with the parameters you want by changing the query parameters in the example url. Parameters `variant`, `window` and `panel` are required query parameters. `r2_thresh` is optional.

Variant needs to be in format chr:pos:ref:alt. Can have chr prefix. X can be X or 23.

Window size is limited to 100000-5000000.

Currently sisu V4.2 (panel parameter value `sisu42`), sisu V4 (panel parameter value `sisu4`) and sisu V3 (panel parameter value `sisu3`) imputation panels are supported. These panels contain the same variants as imputed FinnGen data: sisu3 until data freeze 7, sisu4 in data freezes 8 and 9, sisu4.2 from data freeze 10 onwards.


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# Agent Instructions: Querying This Documentation

If you need additional information that is not directly available in this page, you can query the documentation dynamically by asking a question.

Perform an HTTP GET request on the current page URL with the `ask` query parameter:

```
GET https://docs.finngen.fi/working-outside-the-sandbox/ld-browser.md?ask=<question>
```

The question should be specific, self-contained, and written in natural language.
The response will contain a direct answer to the question and relevant excerpts and sources from the documentation.

Use this mechanism when the answer is not explicitly present in the current page, you need clarification or additional context, or you want to retrieve related documentation sections.