> For the complete documentation index, see [llms.txt](https://docs.finngen.fi/llms.txt). Markdown versions of documentation pages are available by appending `.md` to page URLs; this page is available as [Markdown](https://docs.finngen.fi/working-outside-the-sandbox/risteys-as-an-option-for-browsing-endpoints.md).

# Risteys

[Risteys](https://risteys.finngen.fi) is a useful web portal for understanding FinnGen [endpoints](/finngen-data-specifics/endpoints/finngen-clinical-endpoints.md) and [laboratory measurement](/finngen-data-specifics/red-library-data-individual-level-data/what-phenotype-files-are-available-in-sandbox-1/kanta-lab-values.md) data. Risteys contains data from both [FinRegistry](https://www.finregistry.fi) and [FinnGen](https://www.finngen.fi/en), making it easy to compare the data from both sources side-by-side.

Whereas FinnGen is enriched for diseases and contains **10% of the Finnish population**, which is [**genotyped**](/background-reading/imputation.md), FinRegistry was a research project with a population sample of **\~7 million individuals** (everone alive in 2010 and their parents) with highly similar phenotype data to FinnGen but **no genotype data**.

|             | Number of individuals | Register data                                                                    | Genetic data         | Enrichment                                                                     | Organization             |
| ----------- | --------------------- | -------------------------------------------------------------------------------- | -------------------- | ------------------------------------------------------------------------------ | ------------------------ |
| FinnGen     | 520,210               | Hospital, prescription, KELA reimbursements, primary care + specialty registries | Yes, all individuals | Selected for individuals with medical conditions (clinics, legacy collections) | FinnGen Consortium       |
| FinRegistry | \~7 million           | Same as FinnGen + additional registries such ICUs                                | No                   | General population                                                             | Andrea Ganna's lab & THL |

Risteys is available to everyone at <https://risteys.finngen.fi/> (*no credentials or registration needed*).

A [tutorial](https://risteys.finngen.fi/documentation#tutorial), [how-to section](https://risteys.finngen.fi/documentation#how-to), [explanations](https://risteys.finngen.fi/documentation#explanations), and [methods](https://risteys.finngen.fi/documentation#methods) are found on Risteys website in the [documentation page](https://risteys.finngen.fi/documentation).

If you'd like to see more, please watch these demo videos

* [Risteys FinnGen endpoint browser demo at FinnGen Users' Meeting on 28th of November 2023](https://vimeo.com/user18033117)
* [Rresentation of New FinnGen tools and their application to example diseases from User's meeting 28th March 2023 recording ](https://www.finngen.fi/en/members/recordings/finngen-data-users-meeting-28th-march-2023)(at 25min 23sec) including usage of Risteys.
* Risteys Release 8 update in [FinnGen Data Users' meeting on 14th December 2021](https://www.finngen.fi/en/members/recordings/finngen-users-meeting-14th-december-2021)
* New endpoint explainer in Risteys in [FinnGen Data Users' meeting on 26th January 2021](https://www.finngen.fi/en/members/recordings/finngen-data-users-meeting-26-jan-2021)
* [Risteys tutorial](https://vimeo.com/402146003) (R4, March 2020)

See also frequently asked questions about [Risteys](/faq/about-risteys.md).

On Risteys, you can look up any FinnGen endpoint and obtain:

* **Endpoint Definition** (e.g. *which ICD-10 codes make up the endpoint*)

<div data-full-width="false"><figure><img src="https://3072695768-files.gitbook.io/~/files/v0/b/gitbook-x-prod.appspot.com/o/spaces%2F-MhYL0UTLjqsuIdK0SSO%2Fuploads%2Fgit-blob-789ea582ccbb3315dbc5c7b5d912775b33baabcb%2Fristeys_1.png?alt=media" alt=""><figcaption></figcaption></figure></div>

* **Upset plot detailing case counts by codes** (*opening from the link on the lower right corner near the Endpoint Definition box)*

<figure><img src="https://3072695768-files.gitbook.io/~/files/v0/b/gitbook-x-prod.appspot.com/o/spaces%2F-MhYL0UTLjqsuIdK0SSO%2Fuploads%2Fgit-blob-9e5e6e7e8a4188128565ab2055acbbed02e0fe4e%2Fristeys_2.png?alt=media" alt=""><figcaption></figcaption></figure>

* **Table of case counts by codes** (*opening from the link on the lower right corner near the Endpoint Definition box)*

<figure><img src="https://3072695768-files.gitbook.io/~/files/v0/b/gitbook-x-prod.appspot.com/o/spaces%2F-MhYL0UTLjqsuIdK0SSO%2Fuploads%2Fgit-blob-42fe03784a75f8f10481506cafb975d39d5952ca%2Fristeys_3.png?alt=media" alt=""><figcaption></figcaption></figure>

* **Summary phenotype statistics for the endpoint in both FinnGen data and FinRegistry data** (e.g. *number of cases, age at first event*)

<figure><img src="https://3072695768-files.gitbook.io/~/files/v0/b/gitbook-x-prod.appspot.com/o/spaces%2F-MhYL0UTLjqsuIdK0SSO%2Fuploads%2Fgit-blob-57cb3ac5cb65db4863c4893d9ff05b86e23f3b01%2Freisteys_4.png?alt=media" alt=""><figcaption></figcaption></figure>

<figure><img src="https://3072695768-files.gitbook.io/~/files/v0/b/gitbook-x-prod.appspot.com/o/spaces%2F-MhYL0UTLjqsuIdK0SSO%2Fuploads%2Fgit-blob-9f573a6ede1aa50b91320886dcea8d053d3bc335%2Fristeys_5.1.png?alt=media" alt=""><figcaption></figcaption></figure>

* **Similar endpoints** on Risteys: In addition, it is possible to navigate endpoints by a subset or superset of cases for the current endpoint.

<figure><img src="https://3072695768-files.gitbook.io/~/files/v0/b/gitbook-x-prod.appspot.com/o/spaces%2F-MhYL0UTLjqsuIdK0SSO%2Fuploads%2Fgit-blob-967329d06e892bf8557cacd51cae8d4c3b084511%2Fimage%20(96).png?alt=media" alt=""><figcaption></figcaption></figure>

Risteys also has a section showing the **association between an exposure endpoint and death (FinRegistry data)** and a **Relationships between endpoints** section presenting **survival analysis results from FinRegistry and genetic analyses results from FinnGen**.

<figure><img src="https://3072695768-files.gitbook.io/~/files/v0/b/gitbook-x-prod.appspot.com/o/spaces%2F-MhYL0UTLjqsuIdK0SSO%2Fuploads%2Fgit-blob-8736cc12e601648811651390500dfd2038a00019%2Fristeys_7.png?alt=media" alt=""><figcaption><p>You can press the "?" -button in Risteys to get more information about these sections</p></figcaption></figure>

<figure><img src="https://3072695768-files.gitbook.io/~/files/v0/b/gitbook-x-prod.appspot.com/o/spaces%2F-MhYL0UTLjqsuIdK0SSO%2Fuploads%2Fgit-blob-61cdc222c5b37a2fabb68601f0d8931f4112c0e0%2Fristeys_8.png?alt=media" alt=""><figcaption></figcaption></figure>

On top of the page, Risteys provides links to the [Endpoint Browser](/working-outside-the-sandbox/endpoint-browser.md) and [PheWeb](/working-outside-the-sandbox/link-to-how-to-use-pheweb.md) pages of the endpoint opened in Risteys. The [Endpoint Browser](/working-outside-the-sandbox/endpoint-browser.md) is a tool to visualize hierarchy and relatedness between similar endpoints. The [PheWeb](/working-outside-the-sandbox/link-to-how-to-use-pheweb.md) provides GWAS results for the endpoint.

<figure><img src="https://3072695768-files.gitbook.io/~/files/v0/b/gitbook-x-prod.appspot.com/o/spaces%2F-MhYL0UTLjqsuIdK0SSO%2Fuploads%2Fgit-blob-60507d2a278cc2eb4a917e1c5719b9c8531d8b8a%2Fimage%20(63).png?alt=media" alt=""><figcaption></figcaption></figure>

**Risteys of previous data releases can be found under the arrow menu (see below):**

<figure><img src="https://3072695768-files.gitbook.io/~/files/v0/b/gitbook-x-prod.appspot.com/o/spaces%2F-MhYL0UTLjqsuIdK0SSO%2Fuploads%2FJFyXUFggiuiFd0h8t0lv%2Fimage.png?alt=media&amp;token=749c092e-c3f1-4133-8787-f2ddae02ec9c" alt=""><figcaption></figcaption></figure>