Pairwise endpoint genetic correlation format
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This pipeline produces a single file, containing all pairwise genetic correlations between multiple phenotypes.
Its name is structured as finngen_R[?]_[EUR/FIN].ldsc.summary.tsv
where EUR/FIN changes based on the LD panel used.
(This refers to genetic correlation, in you can also see the number of shared cases between endpoints.)
Column name
Description
p1
Phenotype 1
p2
Phenotype 2
rg
Genetic correlation
se
Standard error
z
z-score
p
pvalue
h2_obs
heritabilty of p1
h2_obs_se
SE of heritability of p1
h2_int
heritability intercept for p1
h2_int_se
SE of intercept
gcov_int
intercept of genetic covariance
gcov_int_se
SE of gcov
CONVERGED
A flag if the LDSC model converged